Priority areas - Anticoagulants in atrial fibrillation

Data from the 2019-2020 Sentinel Stroke Audit highlights that 64% of patients across Wales, England and Northern Ireland with known atrial fibrillation prior to a stroke, were on anticoagulant medication. Although this figure has increased in recent years, there is still a large proportion of patients with known AF that are at greater risk of stroke as they are not anticoagulated, therefore highlighting the need to identify and review these patients.

Patients with AF who have refused anticoagulation should review this decision in conjunction with their prescriber at least annually.

Image of table summarising details for the anticoagulants in atrial fibrillation indicator

Accessible friendly version

  • Atrial fibrillation causes around 20% of strokes, however this can be reduced by about two thirds if people are anticoagulated.
  • NICE guidelines recommend that patients with atrial fibrillation are assessed for stroke risk using the CHA2DS2VASc score.
  • Adults with non-valvular atrial fibrillation and a CHA2DS2VASc score of 2 or above are at a much higher risk of having a stroke than the general population, and should therefore receive anticoagulation.
  • NICE recommends anticoagulation with either apixaban, dabigatran etexilate, edoxaban, rivaroxaban or a Vitamin K antagonist.

Percentage of patients with AF who are prescribed an anticoagulant and have received an anticoagulant review within the last 12 months


Accessible friendly version 

Please note, this data is currently only available up to March 2019 and is therefore in the former health board structures.

 How can changes be made ?

  • Patients with persistent or permanent AF should be assessed for stroke risk using the CHA2DS2VASc score.
  • For patients with a CHA2DS2VASc of 2 or above, anticoagulation should be offered, taking the patient’s bleeding risk into account.



This website uses cookies to ensure you get the best experience, please accept these so we can deliver a more reliable service.

Manage preferences